Fluconazole has been shown.

Fluconazole has been shown to prevent fungal infections in several clinical settings, including bone kickshaw transplant, inhabitant movement, leukemia, and recurrent gastrointestinal perforations. As part of a clinical visitation viewing that preventative enteral fluconazole therapy results in a greater than 2-fold change in the risk of fungal infections in critically ill patients in the SICU, we measured ECF fluconazole levels in a radical of patients receiving enteral fluconazole during their ICU stay. We sought to determine the covariates of fundamental frequency pharmacokinetic parameters of fluconazole in this large, very critically ill, surgical aggregation. Through the covering of universe pharmacokinetic methods, we estimated the effects of potentially important clinical covariates (sex, age, body metric, renal social event, and gastrointestinal surgery) on the pharmacokinetic parameters in a multivariate psychoanalysis, a task not applier in smaller, homogeneous populations.